STEROIDS HORMONES

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When this topic was assigned to me, the first thing that came up into my mind was the boxing champion “Manny Pacquio”.After Manny Pacquiao brutalized his opponents even after moving up in weight class, he was accused of using steroids or performance enhancing drugs. Nowadays, many sports athletes are using steroids to enhance their performance in their respective sports. And to give you some information about Steriods, for everybody’s information, steroids are lipid molecules that act as hormones in our body, and to have some more ideas and knowledge continue reading my topic about steroids hormones.

Steroids hormones differ because these are derived from cholesterols in the gonads and adrenal glands and these are fat soluble substances. Its cell membrane is composed of phospholipid bilayer.



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Steroid Hormone Mechanism of Action



1. First, they pass through the cell membrane of the target cell.

2. Then binds with a specific receptor in the cytoplasm.

3. The receptor bound steroid hormones go into the nucleus and unites to another specific receptor.

4. And the production of protein molecules was done by the steroid hormone-receptor complex.



Steroids hormones are categorized into 5 classes, these are: estrogens,androgens, progesterones, glucocorticoids and mineralocorticoids.



• Androgen

 Start off in the adrenal cortex and gonads

 Primarily affects the function and maturation of the secondary sex organs.

• Estrogens

 Adrenal cortex and gonads

 For maturation and function of the female secondary sex organs.

• Progesterone

 Placenta and ovaries

 menstrual cycle and maintain pregnancy

• Glucocorticoids

 Adrenal Cortex

 Affects metabolism

• Mineralocorticoids

 Adrenal Cortex

 Watere and salt balance





http://biology.about.com/od/cellularprocesses/a/aa073004a.htm

http://www.isteroids.com/Steroid_hormones.html

http://www.cs.stedwards.edu/chem/Chemistry/CHEM43/CHEM43/Steroids/Steroids.HTML